Bone

Bone 01 Jan 2013

Bone Regeneration Using Stromal Cells

This study will evaluate the possible use of bone marrow stromal cells-a type of cell related to bone and fibrous tissue-for jaw bone grafting. When a tooth is lost or removed, there is usually a gradual loss of bony tissue from the jawbone at the site of the missing tooth.
Bone 01 Jan 2013

Shoe Insert Study

This trial will test shoe inserts for the treatment of knee osteoarthritis, the most common form of knee arthritis. Those with disease on the inner (medial) aspect of the knee will be studied. Official Title Randomized Trial of a Wedged Insole for Treatment of Osteoarthritis of the Knee Conditions –…
Bone 01 Jan 2013

Genetic Determinants of Ankylosing Spondylitis Severity

This study will explore how genes-units of heredity-may influence the severity of ankylosing spondylitis. It will examine whether some genes may cause people with ankylosing spondylitis to have more rapid fusion of the bones of the spine, more difficulty performing daily activities, or be more likely to need joint surgery.
Bone 01 Jan 2013

Study of Arthritis and Related Conditions

The purpose of this study is to learn more about the causes of rheumatoid arthritis, juvenile rheumatoid arthritis and related conditions and the course of these diseases. Patients in this study will not receive treatment, but may be offered participation in a treatment protocol if an appropriate study is available.
Bone 01 Jan 2013

Literacy in Arthritis Management

This study will test a new patient education program designed for people who do not read well. It will also look at how poor reading skills affect a person’s health and how people who do not read well learn best. We will randomly assign patients who have a rheumatic condition…
Bone 01 Jan 2013

Diagnostic Study of Patients With Ewing’s Sarcoma

RATIONALE: Genetic testing may help predict how cancer will respond to treatment and allow doctors to plan more effective therapy. PURPOSE: Diagnostic trial to study genetic differences in patients who have Ewing’s sarcoma. RATIONALE: Genetic testing may help predict how cancer will respond to treatment and allow doctors to…
Bone 01 Jan 2013

Effects of HIV on the Development and Function of Bone Marrow Cells

This study will examine the effects of HIV on bone marrow cells. Various types of cells from bone marrow will be studied to learn which cells become infected with HIV, what changes occur in the number of or growth patterns of the cells, what kinds of proteins the cells make…
Bone 01 Jan 2013

Spine Patient Outcomes Research Trial (SPORT) – Intervertebral Disc Herniation

This study tests the effectiveness of different treatments for the three most commonly diagnosed lumbar (lower) spine conditions. The purpose of the study is to learn which of two commonly prescribed treatments (surgery and non-surgical therapy) works better for specific types of low back pain. This study tests the effectiveness…
Look AHEAD
Bone 01 Jan 2013

Look AHEAD

Purpose The Look AHEAD study is a multicenter, randomized clinical trial to examine the long-term effects of a lifestyle intervention designed to achieve and maintain weight loss. The study will investigate the effects of the intervention on heart attacks, stroke and cardiovascular-related death in individuals with type 2 diabetes…