Cancer
01 Jan 2013
AZD0530 Phase II Study in Patients With Advanced Ovarian Cancer (OVERT-1)
The main purpose of this study is to determine if AZD0530 can improve the efficacy of standard chemotherapy for the treatment of ovarian cancer. Official Title A Phase II, Double-Blind, Placebo-Controlled, Multi-Centre, Randomised Study of AZD0530 in Patients With Advanced Ovarian Cancer Sensitive to Platinum-Based Chemotherapy. Conditions…
Cancer
01 Jan 2013
Diagnostic Study of Patients With Stage I Testicular Cancer
Rationale: Diagnostic procedures may improve a doctor’s ability to predict the recurrence of testicular cancer.Purpose: Diagnostic trial to detect the risk of recurrent disease in patients who have stage I testicular cancer and who have undergone orchiectomy within the previous 12 weeks. Official Title Correlation of Histopathology, Immunohistochemistry and Quantitative…
Heart
01 Jan 2013
An Investigation of N-Acetylcysteine and Fenoldopam as Renal Protection Agents for Cardiac Surgery
Patients with abnormal kidney function are at increased risk for complications following heart surgery, including worsening kidney function possibly requiring dialysis, a prolonged stay in the critical care unit and hospital, and the increased risk of death. Prior attempts at kidney protection for heart surgery patients have had mixed results.
Research and Trials
01 Jan 2013
Slings and Their Effect on Skin Pressure
There are many reasons that cause skin to breakdown. This study will only compare pressure, pH and temperature with the use of slings and without the use of slings (fabricated device used to safely handle patient transfers and repositioning).There will be no difference in skin pressure, pH, or temperature with…
Chronic Pain
01 Jan 2013
Treatment of Insomnia Secondary to Chronic Pain
Several studies have shown that behavioural therapy for chronic pain can be beneficial for chronic pain and that behavioural therapy for insomnia can be beneficial for insomnia. However, seldom do chronic pain patients with insomnia receive a behavioural treatment for insomnia. The purpose of this study is to evaluate whether…
Chronic Pain
01 Jan 2013
Proposal to Evaluate the Efficacy of the InterX 5000 in the Treatment of Chronic Neck and Shoulder Pain
The purpose of the proposed study is to evaluate the efficacy of the InterX 5000 in relieving chronic neck and shoulder pain. This study will focus on the efficacy of treating patients who have functional limitations in activity because of chronic/recurrent neck or shoulder pain. H1: InterX therapy will have…
Chronic Pain
01 Jan 2013
Efficacy Study of Prolotherapy vs Corticosteroid for Tennis Elbow
The purpose of the research is to study the effects of two different injection therapies for the treatment of lateral epicondylitis (tennis elbow). Specifically, we will look at which therapy provides better short and long-term relief of pain, which treatment allows better function and less disability, and which treatment gives…
Chronic Pain
01 Jan 2013
Advancement of Psychophysics of Pain Modulation From Lab to Clinic: Constructing Susceptibility Profile for Appearance of Postoperative Neuropathic Pain
Recent advances in the field of pain psychophysics that have enhanced the understanding of pain processing by the nervous system seem to characterise the individual pattern of pain processing, thereby enabling the prediction of a person’s susceptibility to develop chronic pain consequent to surgery. In this project, the researchers propose…
Chronic Pain
01 Jan 2013
Intra-Articular Injection of Botulinum Toxin Type A for Shoulder Pain
The purpose of this study is to determine whether intra-articular botulinum toxin type A is effective in the treatment of chronic joint pain. Official Title Intra-Articular Injection of Botulinum Toxin Type A for the Treatment of Shoulder Pain: A Randomized, Double Blinded, Placebo Controlled Trial. Conditions Arthritis Shoulder…