Research and Trials
01 Jan 2013
Autologous Engineered Skin Substitutes for Closure of Skin Wounds
This clinical trial tests the hypothesis that engineered human skin can reduce the requirements for harvesting of conventional skin autografts by providing more skin for grafting from the donor skin used to treat the wounds. In life-threatening burns (e.g. greater than 50% of the total body surface area), greater availability…
Research and Trials
01 Jan 2013
Skin Tolerance Study of Betamethasone Creams in Atopic Eczema and the Preventative Properties of a Moisturiser
Topical steroid creams as well as moisturising creams are important parts of the treatment strategy of atopic eczema. This study aims to investigare the tolerance of a new strong steroid cream in comparison to an already marketed reference cream with equal amount of active but with different cream vehicle. The…
Joints
01 Jan 2013
Study of Sutures Versus Staples for Skin Closure After Surgical Procedures of Hip
Skin closure either by sutures or staples is required after any surgical procedure of the hip.The purpose of this study is to compare the amount of drainage between patients who have had either staples or sutures placed for skin closure. Official Title A Comparative Randomized Efficacy Study of Sutures Versus…
Research and Trials
01 Jan 2013
Effects of Anthocyanin on Skin Health and Markers of Cardiovascular Disease Risk
The purpose of this study is to determine whether short-term exposure to a compound found in some fruits and vegetables (anthocyanin), is effective in improving skin health and reducing the levels of various markers of cardiovascular disease risk. A range of skin health parameters are being studied and volunteers are…
Research and Trials
01 Jan 2013
Slings and Their Effect on Skin Pressure
There are many reasons that cause skin to breakdown. This study will only compare pressure, pH and temperature with the use of slings and without the use of slings (fabricated device used to safely handle patient transfers and repositioning).There will be no difference in skin pressure, pH, or temperature with…
Cancer
01 Jan 2013
Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That is Metastatic to the Brain
Rationale: Drugs used in chemotherapy use different ways to stop tumour cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumour cells. It is not yet known if chemotherapy is more effective with or without radiation therapy in treating brain metastases.Purpose: Randomised phase…
Men's Health
01 Jan 2013
A Study With ASP2151 in Subjects With Recurrent Episodes of Genital Herpes
A study of ASP2151 in subjects with recurrent outbreaks of genital herpes. Official Title A Phase II, Dose-Finding Study With ASP2151 in Subjects With Recurrent Episodes of Genital Herpes. Conditions Herpes Genitalis Study Type Interventional Study Design Treatment, Randomised, Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Placebo Control, Parallel Assignment,…
Cancer
01 Jan 2013
Intralesional PV-10 Chemoablation of Metastatic Melanoma
The objective of this study is to investigate the safety of intralesional (IL) PV-10 for the treatment of metastatic melanoma. This study will also include a preliminary assessment of response of treated and untreated lesions by clinical evaluation at follow-up of 12 to 24 weeks following IL PV-10 treatment. Official…
Cancer
01 Jan 2013
Study of “NY-ESO-1 ISCOMATRIX” in Patients With High-Risk, Resected Melanoma
The purpose of this trial is to assess whether treatment with “NY-ESO-1 ISCOMATRIX” vaccine improves outcomes for people with Malignant Melanoma which has been removed, but is at high risk of relapse. Official Title Randomized, Double-Blind Phase II Trial of “NY-ESO-1 ISCOMATRIX” Vaccine and “ISCOMATRIX” Adjuvant Alone in Patients With…
