Heart
01 Jan 2013
The Effect of Atorvastatin on Postoperative Renal Function After Cardiac Surgery
Atorvastatin might reduce the oxidative stress that occurs during cardiopulmonary bypass, and thus, prevent or reduce the magnitude of acute kidney dysfunction in those patients…
Heart
01 Jan 2013
The Study of Atherosclerosis with Ramipril and Rosiglitazone
The purpose of this study is to determine if ramipril and/or rosiglitazone retard the progression of atherosclerosis as evaluated by serial carotid intermedial thickness measurements. Official Title The Study of Atherosclerosis With Ramipril and Rosiglitazone. Conditions Atherosclerosis Impaired Glucose Tolerance Isolated Impaired Fasting Glucose Cardiovascular Disease Study Type…
Heart
01 Jan 2013
The DIAMOND Study: Distensibility Improvement and Remodeling in Diastolic Heart Failure
The purpose of this study is to test the hypothesis that treatment with oral ALT-711 twice daily for 16 weeks will improve aortic distensibility, exercise tolerance, and quality of life in elderly patients with isolated diastolic heart failure (DHF), and that the improvements in exercise tolerance will correlate with the…
Heart
01 Jan 2013
An Investigation of N-Acetylcysteine and Fenoldopam as Renal Protection Agents for Cardiac Surgery
Patients with abnormal kidney function are at increased risk for complications following heart surgery, including worsening kidney function possibly requiring dialysis, a prolonged stay in the critical care unit and hospital, and the increased risk of death. Prior attempts at kidney protection for heart surgery patients have had mixed results.
Heart
01 Jan 2013
Identification of Genetic Markers for Cardiopulmonary Diseases (Genotype)
This study is designed to investigate whether an association exists between certain genes/protein levels and the development of various cardiopulmonary diseases. It is hoped that this project will provide valuable insight into the understanding of these diseases. Official Title Identification of Genetic Markers for Cardiopulmonary Diseases. Conditions Cardiovascular Diseases…
Children's health
01 Jan 2013
Patterns of Coronary Artery Anatomy in Children With Congenital Heart Disease by Computed Tomography
Patterns of Coronary Artery Anatomy in Children With Congenital Heart Disease by Computed Tomography Official Title Patterns of Coronary Artery Anatomy in Children With Congenital Heart Disease by Computed Tomography. Conditions Heart Diseases Study Type Interventional Study Design Diagnostic, Non-Randomised, Open Label, Uncontrolled, Parallel Assignment. Further Details Primary…
Heart
01 Jan 2013
Angiotensin II Receptor Blockers (ARB) and ACE Inhibitors (ACEI) on Silent Brain Infarction and Cognitive Decline
The purpose of this study is to elucidate whether or not angiotensin II receptor blockers (ARB) are more beneficial or equal to angiotensin converting enzyme inhibitors (ACEI) on development or progression of silent brain infarction and cognitive decline in Japanese patients with essential hypertension in the elderly. Official Title Effects…
Blood
01 Jan 2013
Sequestration of Platelets Prior to Bypass Reduces Bleeding After Cardiac Surgery
Excessive bleeding is common after cardiac surgery. This may result in patients receiving a blood transfusion or suffering the life-threatening complication of cardiac tamponade. Tamponade is when excessive bleeding compresses the heart and prevents it from pumping properly. A major reason for the bleeding is the damage done to platelets…
Blood
01 Jan 2013
Ezetimibe/Simvastatin in Patients With Metabolic Syndrome
A 6-week clinical trial in patients with metabolic syndrome and hypercholesterolemia at high risk for coronary heart disease to study the effects of ezetimibe/simvastatin and atorvastatin on lipids. Official Title A Multicenter, Randomized, Double-Blind, Parallel Arm, 6-Week Study to Evaluate the Efficacy and Safety of Ezetimibe/Simvastatin Versus Atorvastatin in Patients…
