Bone
01 Jan 2013
Diagnostic Study of Patients With Ewing’s Sarcoma
RATIONALE: Genetic testing may help predict how cancer will respond to treatment and allow doctors to plan more effective therapy. PURPOSE: Diagnostic trial to study genetic differences in patients who have Ewing’s sarcoma. RATIONALE: Genetic testing may help predict how cancer will respond to treatment and allow doctors to…
Infections
01 Jan 2013
Genetics of Hepatitis C Virus Infection
The course of hepatitis C varies among people infected with the virus. Some people respond to treatment while many do not; some recover completely while others remain chronically infected; and among those who remain infected, some have mild symptoms while others’ symptoms are severe. This study will look for genetic…
Bone
01 Jan 2013
Effects of HIV on the Development and Function of Bone Marrow Cells
This study will examine the effects of HIV on bone marrow cells. Various types of cells from bone marrow will be studied to learn which cells become infected with HIV, what changes occur in the number of or growth patterns of the cells, what kinds of proteins the cells make…
Cancer
01 Jan 2013
Radiation Therapy in Patients With Limited-Stage Small Cell Lung Cancer in Complete Remission
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells and prevent the spread of cancer to the brain. It is not yet known if standard-dose radiation therapy is more effective than high-dose radiation therapy in preventing the spread of limited-stage small cell lung cancer cells to the brain. Official…
Infections
01 Jan 2013
Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection
This study will evaluate hepatitis C virus (HCV) infection in blood donors who test positive for antibodies to this virus. Most HCV-infected people do not become ill and are not aware that they have hepatitis or have had it in the past. Some infected people recover completely, whereas others remain…
Infections
01 Jan 2013
A Study of Patients Who Recently Have Been Infected with HIV
The purpose of this study is to find out if anti-HIV drugs, taken by patients who are newly infected with HIV, can make the level of HIV in the body too low to detect. Studying patients who recently have been infected with HIV may help researchers understand how HIV infection…
Gastro
01 Jan 2013
Dietary Macronutrients and Weight Loss
To test the effectiveness for weight loss and weight maintenance of four diets differing in macronutrient composition: moderate in fat (35 percent energy) with two different protein levels (15 percent and 25 percent), and low in fat (20 percent energy), also with 15 percent and 25 percent protein. Official Title…
Hormones
01 Jan 2013
A Study To Evaluate The Safety And Efficacy Of An Investigational Diabetes Drug In Poorly Controlled Type II Diabetics
The purpose of this research study is to determine if a new investigational diabetes drug is safe and effective in treating people who have Type II diabetes mellitus with very high HbA1c or FPG (fasting plasma glucose) levels. The HbA1c test, also called the hemoglobin A1c test or glycated hemoglobin…
Blood
01 Jan 2013
Study of Combination Thalidomide Plus Glucocorticoid Therapy Versus Glucocorticoid Therapy Alone as Induction Therapy for Previously Untreated Subjects with Multiple Myeloma
Randomized subjects will receive study drug, either thalidomide plus high-dose dexamethasone or placebo identical in appearance to thalidomide plus high-dose dexamethasone, in 4-week cycles. Subjects will remain on study drug until they experience disease progression or until the subject discontinues for any other reason. Subjects will have visits every cycle…
