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Nexavar-Tarceva Combination Therapy for First Line Treatment of Patients Diagnosed With Hepatocellular Carcinoma

This is a randomised trial to evaluate the clinical benefit of sorafenib and erlotinib versus sorafenib and placebo in subjects with unresectable advanced or metastatic Child-Pugh A…

01 Jan 2013

The Effect of Atorvastatin on Postoperative Renal Function After Cardiac Surgery

Atorvastatin might reduce the oxidative stress that occurs during cardiopulmonary bypass, and thus, prevent or reduce the magnitude of acute kidney dysfunction in those patients…

01 Jan 2013

Safety and Efficacy Study of MPC-4326 for Treatment of Patients With HIV-1 Infection

Safety and Efficacy Study of MPC-4326 for Treatment of Patients With HIV-1 Infection

To evaluate the antiretroviral activity and safety of 200 mg BID and 300 mg BID doses of MPC-4326 administered as monotherapy for 14 days to…

01 Jan 2013

A Study of Avastin (Bevacizumab) in Combination With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Glioblastoma

A Study of Avastin (Bevacizumab) in Combination With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Glioblastoma

This two-arm study will investigate the efficacy and safety of the addition of bevacizumab (Avastin) to the current standard of…

01 Jan 2013

A Clinical Trial of CSL’s 2009 H1N1 Influenza Vaccine (CSL425) in Healthy Children

The purpose of this study is to determine whether CSL425 is a safe and effective vaccine for eliciting an immune response to H1N1 influenza in…

01 Jan 2013

Safety Study of CSL Limited’s Influenza Virus Vaccine in the Paediatric Population

A Phase IV, Open Label, Multi-Centre Study to Evaluate the Safety and Tolerability of CSL Limited's Influenza Virus Vaccine in a Paediatric Population Aged >=…

01 Jan 2013

Repeat Dose Safety Study for Compound to Treat Anaemia

Repeat Dose Safety Study for Compound to Treat Anaemia

The purpose of this study is to characterise the safety and tolerability of repeat doses of compound 1278863A in healthy subjects.

01 Jan 2013

A Study Evaluating Safety and Immunogenicity of Meningococcal B rLP2086 Vaccine in Adolescents

The purpose of this study is to evaluate the safety and immunogenicity of an investigational meningococcal B rLP2086 vaccine in adolescents aged 11 to 18…

01 Jan 2013

Lume Lung 2: BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC

The trial will be performed to evaluate if BIBF 1120 in combination with standard pemetrexed therapy is more effective than placebo plus standard pemetrexed therapy…

01 Jan 2013