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Trial in Locally Advanced and Metastatic Adrenocortical Carcinoma Treatment (FIRM-ACT)

The purpose of this study is to determine whether treatment with etoposide, doxorubicin, cisplatin and mitotane (EDP/M) prolongs survival as…

01 Jan 2013

Combination Chemotherapy After Surgery in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer

Combination Chemotherapy After Surgery in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.

01 Jan 2013

Study of irinotecan (CPT-11) combined with fixed dose of 5-fluorouracil (5-FU) adult patients with advanced solid tumours

Advanced solid tumors (gastrointestinal incl. Colorectal, head & neck, others) (1): to find the maximum tolerated dose (MTD) of the…

01 Jan 2013

Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor

RATIONALE: Sulindac may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth. Hormone therapy…

01 Jan 2013

Treatment of non-Hodgkin’s lymphoma with rituximab plus CHOP chemotherapy: 9-year follow-up

The objective of the study was to present long-term follow-up data with updated time to disease progression (TTP) and duration…

01 Jan 2013

Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects with Active Ankylosing Spondylitis

The objective of this study is to evaluate the safety and efficacy of adalimumab 40mg every other week (eow) compared…

01 Jan 2013

Evaluate the Survival Benefits of Zemplar versus Calcijex in Subjects w/ Stage V Chronic Kidney Disease on Hemodialysis

To evaluate the survival benefit associated with Zemplar therapy as compared to Calcijex for the treatment of secondary hyperparathyroidism in…

01 Jan 2013

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Efficacy, and Pharmacokinetics of the Human Anti-TNF Monoclonal Antibody Adalimumab in Children With Polyarticular Juvenile Rheumatoid Arthritis

This is a multicenter, Phase III randomized, placebo-controlled study in which polyarticular JRA subjects who are either MTX treated or…

01 Jan 2013

Safety of NXY-059 for the Treatment of Patients who have Suffered from a Stroke

Safety of NXY-059 for the Treatment of Patients who have Suffered from a Stroke

This study will determine if NXY-059 is safe in patients with an acute stroke caused by bleeding in the central…

01 Jan 2013