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Dose Ranging Efficacy And Safety With Mepolizumab in Severe Asthma (DREAM)

Dose Ranging Efficacy And Safety With Mepolizumab in Severe Asthma (DREAM)

The purpose of this study is to show whether mepolizumab given every 4 weeks intravenously (i.v.) can reduce the frequency…

01 Jan 2013

Appropriate Oxygen Levels for Extremely Preterm Infants: a Prospective Meta-analysis (NeOProM)

Appropriate Oxygen Levels for Extremely Preterm Infants: a Prospective Meta-analysis (NeOProM)

For over 60 years the most appropriate oxygen level for preterm babies remains unknown. To answer this, we will combine…

01 Jan 2013

A Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Prucalopride (Resolor) Tablets in Subjects With Chronic Constipation

A Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Prucalopride (Resolor) Tablets in Subjects With Chronic Constipation

The purpose of this study is to compare the efficacy and safety of prucalopride 2 mg given orally once daily…

01 Jan 2013

Phase 3 Study of Immunotherapy to Treat Advanced Prostate Cancer

Phase 3 Study of Immunotherapy to Treat Advanced Prostate Cancer

The purpose of this study is to determine if patients with metastatic prostate cancer who have not received chemotherapy live…

01 Jan 2013

Dose-Finding Study of Favipiravir in the Treatment of Uncomplicated Influenza

Dose-Finding Study of Favipiravir in the Treatment of Uncomplicated Influenza

This is a Phase 2, randomized, double-blind, placebo-controlled multicenter study evaluating the efficacy and safety of two doses of favipiravir…

01 Jan 2013

Randomised, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF (ARTEMIS)

Randomised, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF (ARTEMIS)

The ARTEMIS-IPF study is for people who have been diagnosed with IPF and are between 40 and 80 years of age. People who have been…

01 Jan 2013

Nexavar-Tarceva Combination Therapy for First Line Treatment of Patients Diagnosed With Hepatocellular Carcinoma

This is a randomised trial to evaluate the clinical benefit of sorafenib and erlotinib versus sorafenib and placebo in subjects with unresectable advanced or metastatic Child-Pugh A…

01 Jan 2013

The Effect of Atorvastatin on Postoperative Renal Function After Cardiac Surgery

Atorvastatin might reduce the oxidative stress that occurs during cardiopulmonary bypass, and thus, prevent or reduce the magnitude of acute kidney dysfunction in those patients…

01 Jan 2013

Use of TREM-1 Protein to Differentiate Viral and Bacterial Pneumonias in Intubated Children

Use of TREM-1 Protein to Differentiate Viral and Bacterial Pneumonias in Intubated Children

The purpose of this study is to determine whether a protein called TREM-1 can be used to differentiate viral and…

01 Jan 2013