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A Multi-Center Study of E7389 Versus Treatment of Physician’s Choice in Patients With Locally Recurrent or Metastatic Breast Cancer

A Multi-Center Study of E7389 Versus Treatment of Physician’s Choice in Patients With Locally Recurrent or Metastatic Breast Cancer

The primary objective of this study is to compare Overall Survival (OS) in patients treated with E7389 versus the Treatment…

01 Jan 2013

PI-88 and/or Dacarbazine in Treating Patients With Metastatic Melanoma That Cannot Be Removed By Surgery

PI-88 may stop the growth of tumour cells by blocking blood flow to the tumour. Drugs used in chemotherapy, such…

01 Jan 2013

Tirapazamine, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer

Tirapazamine, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer

RATIONALE: Drugs used in chemotherapy, such as tirapazamine and cisplatin, work in different ways to stop the growth of tumor…

01 Jan 2013

Trial in Locally Advanced and Metastatic Adrenocortical Carcinoma Treatment (FIRM-ACT)

The purpose of this study is to determine whether treatment with etoposide, doxorubicin, cisplatin and mitotane (EDP/M) prolongs survival as…

01 Jan 2013

A Feasibility Study to Evaluate Adjuvant Chemoradiotherapy for Gastric Cancer

The purpose of this study is to determine the side-effects and effectiveness of a new type of chemoradiotherapy treatment for…

01 Jan 2013

A Comparison of CS-747 and Clopidogrel in Acute Coronary Syndrome Subjects Who Are to Undergo Percutaneous Coronary Intervention

A Comparison of CS-747 and Clopidogrel in Acute Coronary Syndrome Subjects Who Are to Undergo Percutaneous Coronary Intervention

The sponsors of this investigational drug are developing prasugrel as a possible treatment for patients with acute coronary syndrome (heart…

01 Jan 2013

Pain and Stress Management for People with Rheumatoid Arthritis

Pain and Stress Management for People with Rheumatoid Arthritis

Self-management of rheumatoid arthritis (RA) symptoms using written emotional disclosure (ED), coping skills training (CST), or a combination of both…

01 Jan 2013

Early Antipseudomonal Therapy in Cystic Fibrosis

Early Antipseudomonal Therapy in Cystic Fibrosis

To determine a safe, effective, and systematic approach to antibiotic treatment of Pseudomonas infection in young children with cystic fibrosis.

01 Jan 2013

FOLFOX4 in Patients with Normal and Abnormal Renal Function

This trial is a phase II study of patients with advanced gastrointestinal (GI) malignancies who will be assigned to one…

01 Jan 2013