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PRIME: Panitumumab Randomized Trial In Combination With Chemotherapy for Metastatic Colorectal Cancer to Determine Efficacy

The purpose of this study is to determine the treatment effect of panitumumab in combination with FOLFOX compared to FOLFOX…

01 Jan 2013

Gemcitabine With or Without Erlotinib in Treating Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer

Randomized phase III trial to determine the effectiveness of gemcitabine with and without erlotinib in treating patients who have unresectable…

01 Jan 2013

Pilot Efficacy Study of PI-88 With Docetaxel to Treat Prostate Cancer

Pilot Efficacy Study of PI-88 With Docetaxel to Treat Prostate Cancer

Docetaxel (Taxotere) is an approved chemotherapeutic drug for the treatment of androgen-independent prostate cancer. The aim of the study is…

01 Jan 2013

A Multi-Center Study of E7389 Versus Treatment of Physician’s Choice in Patients With Locally Recurrent or Metastatic Breast Cancer

A Multi-Center Study of E7389 Versus Treatment of Physician’s Choice in Patients With Locally Recurrent or Metastatic Breast Cancer

The primary objective of this study is to compare Overall Survival (OS) in patients treated with E7389 versus the Treatment…

01 Jan 2013

PI-88 and/or Dacarbazine in Treating Patients With Metastatic Melanoma That Cannot Be Removed By Surgery

PI-88 may stop the growth of tumour cells by blocking blood flow to the tumour. Drugs used in chemotherapy, such…

01 Jan 2013

Tirapazamine, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer

Tirapazamine, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer

RATIONALE: Drugs used in chemotherapy, such as tirapazamine and cisplatin, work in different ways to stop the growth of tumor…

01 Jan 2013

Trial in Locally Advanced and Metastatic Adrenocortical Carcinoma Treatment (FIRM-ACT)

The purpose of this study is to determine whether treatment with etoposide, doxorubicin, cisplatin and mitotane (EDP/M) prolongs survival as…

01 Jan 2013

A Feasibility Study to Evaluate Adjuvant Chemoradiotherapy for Gastric Cancer

The purpose of this study is to determine the side-effects and effectiveness of a new type of chemoradiotherapy treatment for…

01 Jan 2013

A Comparison of CS-747 and Clopidogrel in Acute Coronary Syndrome Subjects Who Are to Undergo Percutaneous Coronary Intervention

A Comparison of CS-747 and Clopidogrel in Acute Coronary Syndrome Subjects Who Are to Undergo Percutaneous Coronary Intervention

The sponsors of this investigational drug are developing prasugrel as a possible treatment for patients with acute coronary syndrome (heart…

01 Jan 2013