Dubin-Johnson syndrome is an inherited (autosomal recessive) syndrome in which the liver cannot adequately excrete bilirubin. It causes an increase of conjugated bilirubin without elevating liver enzymes (ALT, AST), associated with a defect in the ability of hepatocytes (liver cells) to secrete conjugated bilirubin into the bile.

Dubin-Johnson syndrome is usually diagnosed in early infancy.

For more information, see Dubin-Johnson Syndrome.

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