Cancer
01 Jan 2013
Breast Cancer Trial of an Investigational Drug Versus Capecitabine in Male or Female Patients With Advanced Breast Cancer
The purpose of this clinical trial is to determine if the investigational drug is a better treatment than capecitabine (Xeloda) for advanced breast cancer in patients that no longer benefit from docetaxel and/or paclitaxel. Official Title A Randomized, Open-Label, Phase III Study of an Investigational Drug IV Every 3 Weeks…
Cancer
01 Jan 2013
A Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon Cancer
This study will compare the efficacy and safety of intermittent oral Xeloda plus Eloxatin with that of fluorouracil/leucovorin in patients who have had surgery for colon cancer and no previous chemotherapy. The anticipated time on study treatment is until disease progression and the target sample size is 500+ individuals. Official…
Cancer
01 Jan 2013
A Multi-Center Study of E7389 Versus Treatment of Physician’s Choice in Patients With Locally Recurrent or Metastatic Breast Cancer
The primary objective of this study is to compare Overall Survival (OS) in patients treated with E7389 versus the Treatment of Physician’s Choice (TPC) in patients with locally recurrent or metastatic breast cancer. Secondary objectives are to assess: Progression Free Survival (PFS) Objective Tumor Response Rate as measured…
Research and Trials
01 Jan 2013
Pneumococcal Vaccination of Australian Indigenous Mothers to See If It Protects Their Babies From Ear Disease
PneuMum: A Randomised Controlled Trial of Pneumococcal Polysaccharide Vaccination for Aboriginal and Torres Strait Islander Mothers to Protect Their Babies From Ear Disease clinical trials…
Cancer
01 Jan 2013
Study to Evaluate the Efficacy of the Human Papillomavirus Vaccine in Healthy Adult Women of 26 Years of Age and Older.
This study will evaluate the immune responses, safety and efficacy of the investigational HPV vaccine in women who are 26 years of age or older. Infection with human papilloma virus (HPV) has been clearly established as the central cause of cervical cancer. Official Title A Study to Evaluate the Safety,…
Research and Trials
01 Jan 2013
Antiviral Activity of Entecavir in Patients Receiving Liver Transplant Due to Chronic Hepatitis B Virus Infection
The purpose of this clinical research study is to learn if the study drug entecavir will prevent the recurrence of hepatitis B virus in subjects who receive an orthotopic liver transplant (OLT). Official Title Study of the Antiviral Activity of Entecavir in Patients Receiving Liver Transplant Due to Chronic Hepatitis…
Research and Trials
01 Jan 2013
Study of a Pandemic Influenza Vaccine in healthy adults
The avian influenza H5N1 virus strain is the leading candidate to cause the next avian influenza pandemic. This study will test the safety and immunogenicity of a H5N1 pandemic influenza vaccine in healthy adults. Official Title Phase Ia Study of a Pandemic Influenza Vaccine Conditions Avian Influenza Study Type Interventional…
Research and Trials
01 Jan 2013
The Pharmacokinetics of Double Boosted Protease Inhibitors in Antiretroviral-Naive HIV-1 Infected Patients
Treatment with only protease inhibitors might benefit HIV patients. Laboratory data have shown that the combination of saquinavir with lopinavir and ritonavir may a good regimen. This study will explore this idea. Official Title Pharmacokinetics of and Rate of HIV-1 RNA Decline in ARV-Naive HIV-1 Infected Patients Treated With Low-…
Research and Trials
01 Jan 2013
Sensory Cues for Freezing in Parkinson’s Disease
The purpose of this study is (1) to determine if patient triggered sensory (auditory, visual and tactile) cues can help treat freezing of gait in Parkinson’s disease, and (2) to assess if unexpected (randomized) cues are more effective than anticipated ones. Official Title Effect of Randomized Patient-Triggered Sensory Cues for…
