Research and Trials
01 Jan 2013
Seizure Advisory System Feasibility Study
The purpose of this prospective, single-arm, unblinded, multicenter clinical study is to evaluate the safety and effectiveness of the NeuroVista Seizure Advisory System (SAS) in patients with medically refractory epilepsy. A total of 10 subjects will be implanted at up to three study sites. Official Title Safety and Effectiveness of…
Research and Trials
01 Jan 2013
Dose-Finding Study of Favipiravir in the Treatment of Uncomplicated Influenza
This is a Phase 2, randomized, double-blind, placebo-controlled multicenter study evaluating the efficacy and safety of two doses of favipiravir in older adult patients with uncomplicated influenza. Official Title A Phase 2, Randomized, Double-Blind, Placebo-Controlled Multicenter Study Evaluating the Efficacy and Safety of Two Doses of Favipiravir in Older Adult…
Cancer
01 Jan 2013
ToGA Study – A Study of Herceptin (Trastuzumab) in Combination With Chemotherapy Compared With Chemotherapy Alone in Patients With HER2-Positive Advanced Gastric Cancer
This parallel, randomized, open-label, multi-centre study will evaluate the effect on overall survival of trastuzumab (Herceptin) in combination with a chemotherapy compared to the chemotherapy alone in patients with HER2-positive advanced gastric cancer. Trastuzumab (Herceptin) will be administered as intravenous infusion of 6 mg/kg (loading dose 8 mg/kg) every 3…
Research and Trials
01 Jan 2013
Safety, Tolerability and Pharmacokinetics of Multiple Doses of ZGN-433 in Obese Female Volunteers
Research and Trials
01 Jan 2013
The CANTATA-MSU Trial (CANagliflozin Treatment and Trial Analysis – Metformin and SUlphonylurea)
The purpose of this study is to evaluate the efficacy and safety of 2 different doses of canagliflozin compared with placebo in patients with type 2 diabetes mellitus who are receiving treatment with metformin and sulphonylurea and have inadequate glycemic (blood sugar) control. Official Title A Randomized, Double-Blind, Placebo-Controlled, 3-Arm,…
Research and Trials
01 Jan 2013
Safety and Efficacy of GS-9350-boosted Atazanavir Versus Ritonavir-boosted Atazanavir in HIV-1 Infected Adults
To evaluate the safety and efficacy of a regimen containing GS-9350-boosted atazanavir plus emtricitabine/tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus emtricitabine/tenofovir disoproxil fumarate in HIV 1 infected, antiretroviral treatment-naïve adults. Development of GS-9350 as a "pharmacoenhancer" could provide a beneficial alternative to ritonavir for use in combination with protease inhibitors.
Research and Trials
01 Jan 2013
Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial (ARISE)
EGDT, compared to standard Australasian resuscitation practice, reduces 90-day all-cause mortality in patients presenting to the ED with severe sepsis.
Cancer
01 Jan 2013
Radiotherapy for Neurotropic Melanoma of the Head and Neck (RTN2)
Melanoma is a serious and common malignancy in Australia. It is the third most common cancer in Australia and approximately 1000 Australians will die of…
Research and Trials
01 Jan 2013
Epstein-Barr Virus (EBV)-Specific T Cells as Therapy for Relapsed/Refractory EBV-Positive Lymphomas (EPL)
This trial will use a new method of treating lymphoma using a therapy derived from a person's Killer T cells.