Bone
11 Jul 2007
New Dynamic Brace Developed to Advance Clubfoot Treatment
A new brace that maintains correction for clubfoot, a birth defect in which the foot is turned in toward the body, has shown better compliance and fewer complications than the traditional brace used to treat the condition. Orthopaedic surgeon Matthew Dobbs describes the differences between a traditional brace for clubfoot…
Children's health
11 Jul 2007
New Clues for Treatment of Disease That Causes Accelerated Aging
There is renewed hope for treatment of a rare genetic condition that causes rapidly accelerated aging and leads to an average life expectancy of 13 years. Scientists studying the genes of two infants who died of mysterious illnesses found the infants had mutations in LMNA, the same gene altered in…
Blood
11 Jul 2007
‘Modular’ Leukaemia Drug Shows Promise in Early Testing
A new type of engineered drug candidate has shown promise in treating chronic lymphocytic leukaemia in both test tube and early animal tests, a new study shows. The agent represents a new class of agents called small modular immunopharmaceuticals. Called CD37-SMIP, the agent targets a protein called CD37 on the…
Children's health
11 Jul 2007
Help Available for Anxious Teens in Rural and Remote Australia
A pioneering research project developed at The University of Queensland will help teenagers in rural and remote areas of Australia to overcome anxiety. Child anxiety expert Professor Sue Spence, together with the BRAVE team, developed the program that can be undertaken over the internet. According to Professor Spence adolescence can…
Blood
11 Jul 2007
Breakthrough in Research and Treatment of Rare But Devastating Condition
Researchers at Queen Mary University London and the University of Leicester announced a potential breakthrough in the treatment of a rare but devastating medical condition that can affect children and young people. In a world first, the clinicians and scientists from the two universities have already treated one patient with…
Children's health
10 Jul 2007
Fever After Smallpox Vaccination Tied to Individual Genetic Variations
St. Louis researchers have identified common DNA variations that underlie susceptibility to fever after smallpox vaccination. Their finding is the first to link individual differences written into the genetic code with a vaccine-related complication – albeit a mild one. Most of the eight genetic alterations the scientists identified increased the…
Blood
09 Jul 2007
Children With Sickle Cell Get Extra Vaccine Benefit
A childhood vaccine known to protect against the bacteria that causes ear infections and pneumonia may well be a lifesaver for children with sickle cell disease. Researchers at the Monroe Carell Jr. Children’s Hospital at Vanderbilt and colleagues at other institutions found that pneumococcal conjugate vaccine (PCV), known commercially as…
Children's health
09 Jul 2007
PCV Cuts Pneumonia Hospital Admissions in the US
Routine infant immunization with pneumococcal conjugate vaccine (PCV7) has caused a 39 percent fall in all-cause pneumonia hospital admission rates for American children under 2, according to a Vanderbilt study. Carlos G. Grijalva, M.D., M.P.H., research assistant professor in Vanderbilt’s Department of Preventive Medicine, along with colleagues in the Vanderbilt…
Children's health
08 Jul 2007
Sudden unexpected death in epilepsy (SUDEP)
Sudden unexpected death in epilepsy (SUDEP) refers to sudden death, with or without epileptic seizure, with no identifiable cause on post mortem.