Chronic Pain
01 Jan 2013
Evaluating Therapeutic Massage for Chronic Neck Pain
Purpose This study will provide the basis for a full-scale trial to evaluate the effectiveness and safety of therapeutic massage for chronic neck pain (CNP). The study will involve two phases: Phase I includes the development of massage and control protocols and the development of appropriate inclusion and exclusion…
Bone
01 Jan 2013
Look AHEAD
Purpose The Look AHEAD study is a multicenter, randomized clinical trial to examine the long-term effects of a lifestyle intervention designed to achieve and maintain weight loss. The study will investigate the effects of the intervention on heart attacks, stroke and cardiovascular-related death in individuals with type 2 diabetes…
Heart
01 Jan 2013
Clinical Trial of Dietary Protein on Blood Pressure
Purpose To examine the effect of dietary protein supplementation on blood pressure. Official Title Conditions – Cardiovascular Diseases- Hypertension- Heart Diseases Study Type Interventional Study Design Prevention, Randomized, Double-Blind, Crossover Assignment Further Details BACKGROUND: At least 50 million adult Americans have hypertension, one of the most important modifiable…
Blood
01 Jan 2013
Aggressive vs. conservative red blood cell transfusion therapy in surgical patients with Cardiovascular Disease
Purpose: To compare aggressive with conservative red blood cell transfusion therapy in surgical patients with cardiovascular disease. Official Title Conditions – Anemia- Blood Disease- Blood Transfusion- Cardiovascular Diseases- Heart Diseases- Myocardial Infarction- Thromboembolism- Pneumonia- Cerebrovascular Accident Study Type Interventional Study Design Preventional, Randomised. Further Details BACKGROUND: Red blood cell…
Cancer
01 Jan 2013
Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow
Purpose The are a variety of cancerous diseases of the blood and bone marrow that can be potentially cured by bone marrow transplantation (BMT). Diseases like leukemia, lymphoma, and multiple myeloma are among the conditions that can be treated with BMT. Official Title Non-myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic…
Infections
01 Jan 2013
Natural History of West Nile Virus Infection
Purpose This study will examine how West Nile virus (WNV) infection affects the body. Some people infected with WNV have no symptoms. In others, symptoms may vary from fever and headache to a polio-like syndrome with paralysis, to coma and brain changes like those of a stroke. Many patients…
Infections
01 Jan 2013
Study of Mycobacterial Infections
Purpose This study will examine the symptoms, course of disease and treatment of non-tuberculous mycobacterial (NTM) infections, as well as the genetics involved in these infections. Patients with NTM have recurrent lung infections and sometimes infections of the skin and other organs as well. They may also have curvature…
Heart
01 Jan 2013
Effect of B blockade on haemodynamics and brain natriuretic peptide (BNP)
The aim of the study is to test the effects of Atenolol, Pindolol and Nebivolol on central blood pressure and augmentation index. Studies of normotensive and hypertensive individuals have confirmed that pulse pressure is a better predictor of cardiovascular events than mean pressure in older adults. Official Title Conditions Study…
Heart
01 Jan 2013
Perioperative stress response in infants undergoing cardiac surgery: a comparison of three alfentanil dosage regimens
Perioperative stress response in infants undergoing cardiac surgery: a comparison of three alfentanil dosage regimens Official Title Conditions Study Type Study Design Further Details What is the smallest dose of alfentanil that minimises neuro-hormonal stress response in infants undergoing cardiac surgery? 90 infants aged less than 1 year undergoing palliative…
