Mental Health
01 Jan 2013
Treatment Of Resistant Depression In Adolescents (TORDIA)
This is a study of depression in adolescents, ages 12 to 18, who are currently taking a prescribed selective serotonin reuptake inhibitor (SSRI) antidepressant medication but are still experiencing depression. The purpose of the study is to determine how best to treat adolescents with depression that is “resistant” to the…
Infections
01 Jan 2013
Cytotoxic T-Lymphocytes for the Prophylaxis of Cytomegalovirus after Allogeneic Stem Cell Transplant
Patients enrolled on this study have a type of blood cell cancer, other blood disease or a genetic disease for which they will receive a stem cell transplant. The donor of the stem cells will be either a brother or sister or another relative or a closely matched unrelated donor.
Hormones
01 Jan 2013
Long Term Post Operative Follow-Up of Cushing Syndrome
Although most patients with hypercortisolism can be diagnosed and treated the long-term effects of hypercortisolism and its treatment are unknown. Official Title Long-Term Post-Operative Follow-Up of Cushing Syndrome Conditions – Cushing Syndrome Study Type Observational Study Design Natural History Further Details This study will attempt to answer the following…
Gastro
01 Jan 2013
G-CSF to Treat Crohn’s Disease
This study will examine the effectiveness of G-CSF in treating patients with Crohn’s disease-a long-term recurring inflammation of the small and large intestine. Patients may have swelling and bleeding of the intestinal lining, which can lead to infection and abdominal pain, weight loss, fever, diarrhea, bloody stools, fistula (connections between…
Gastro
01 Jan 2013
Parasitic Infections of the Gastrointestinal Tract
This protocol offers diagnosis and standard medical treatment for various parasitic gastrointestinal infections. Gastrointestinal parasites are either worms (helminths) or one-celled animals called protozoans which live in the human intestines. Often, parasitic infections do not cause illness. In these cases, drug treatment is not indicated, because treatment can have adverse…
Infections
01 Jan 2013
Randomized Study of Two Doses of Oral Valacyclovir in Immunocompromised Patients With Uncomplicated Herpes Zoster
OBJECTIVES: I. Compare the efficacy and safety of two doses of oral valacyclovir in immunocompromised patients with uncomplicated herpes zoster. II. Compare quality of life, pain, and medical resource utilization in patients treated with these 2 regimens. OBJECTIVES:I. Compare the efficacy and safety of two doses of oral valacyclovir…
Infections
01 Jan 2013
HERPEVAC Trial for Women
The primary purpose of this study is to see if the vaccine is safe and prevents genital herpes disease in women who are not infected. The primary purpose of this study is to see if the vaccine is safe and prevents genital herpes disease in women who are not infected.
Infections
01 Jan 2013
Treating Severe Chronic EBV Infection with EBV Specific CTLs
Severe chronic active Ebstein-Barr virus (SCAEBV) is a rare Epstein-Barr virus (EBV or commonly known as mono or the kissing disease) associated disorder. This disorder may cause chronic tiredness and fevers and sometimes be complicated by life threatening problems such as multi-organ failure, chronic (ongoing) pneumonia, and lymphoproliferative diseases (diseases…
Blood
01 Jan 2013
Tipifarnib in Treating Patients With Myelofibrosis and Myeloid Metaplasia
RATIONALE: Tipifarnib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. PURPOSE: Phase II trial to study the effectiveness of tipifarnib in treating patients who have myelofibrosis with myeloidmetaplasia. Condition: – chronic idiopathic myelofibrosis – Polycythemia Vera – Essential Thrombocythemia…
