Heart
01 Jan 2013
Periodontitis and Cardiovascular Events or
The purpose of this study is to determine if treating periodontal infections (gum problems) will lead to fewer heart problems in patients at high risk for cardiovascular disease. Official Title Periodontal Intervention for Cardiac Events: A Pilot Trial Conditions – Cardiovascular Disease- Coronary Heart Disease- Myocardial Infarction- Cerebrovascular Accident…
Cancer
01 Jan 2013
Radiation Therapy in Patients With Limited-Stage Small Cell Lung Cancer in Complete Remission
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells and prevent the spread of cancer to the brain. It is not yet known if standard-dose radiation therapy is more effective than high-dose radiation therapy in preventing the spread of limited-stage small cell lung cancer cells to the brain. Official…
Infections
01 Jan 2013
Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection
This study will evaluate hepatitis C virus (HCV) infection in blood donors who test positive for antibodies to this virus. Most HCV-infected people do not become ill and are not aware that they have hepatitis or have had it in the past. Some infected people recover completely, whereas others remain…
Infections
01 Jan 2013
A Study of Patients Who Recently Have Been Infected with HIV
The purpose of this study is to find out if anti-HIV drugs, taken by patients who are newly infected with HIV, can make the level of HIV in the body too low to detect. Studying patients who recently have been infected with HIV may help researchers understand how HIV infection…
Gastro
01 Jan 2013
Dietary Macronutrients and Weight Loss
To test the effectiveness for weight loss and weight maintenance of four diets differing in macronutrient composition: moderate in fat (35 percent energy) with two different protein levels (15 percent and 25 percent), and low in fat (20 percent energy), also with 15 percent and 25 percent protein. Official Title…
Cancer
01 Jan 2013
Surgery in Treating Children With Neuroblastoma
RATIONALE: Surgery alone may be effective in treating children with neuroblastoma. PURPOSE: Phase III trial to study the effectiveness of surgery alone in treating children who have neuroblastoma. Official Title Phase III Study of Primary Surgical Therapy in Children With Low-Risk Neuroblastoma Conditions – localized resectable neuroblastoma- stage 4S neuroblastoma…
Infections
01 Jan 2013
Pegasys in Combination with Copegus in Previously Untreated Patients with Chronic Hepatitis C Virus Genotype 2 or 3
The objective of this study is to evaluate the efficacy and safety of Pegasys in combination with Copegus given for 16 weeks versus 24 weeks in previously untreated patients with Chronic Hepatitis C virus Genotype 2 or 3. Official Title Evaluation of the efficacy and safety of Pegasys in combination…
Cancer
01 Jan 2013
Irinotecan in Treating Children With Refractory Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Official Title Phase II Study of Irinotecan in Children With Refractory CNS or Solid Tumors Conditions Condition: – Ewing’s family of tumors- childhood brain tumor- childhood rhabdomyosarcoma- childhood solid tumor-…
Hormones
01 Jan 2013
A Study To Evaluate The Safety And Efficacy Of An Investigational Diabetes Drug In Poorly Controlled Type II Diabetics
The purpose of this research study is to determine if a new investigational diabetes drug is safe and effective in treating people who have Type II diabetes mellitus with very high HbA1c or FPG (fasting plasma glucose) levels. The HbA1c test, also called the hemoglobin A1c test or glycated hemoglobin…
