Heart
01 Jan 2013
Efficacy and Safety of Azimilide in the Prophylactic Treatment of Patients With Atrial Fibrillation
Atrial fibrillation (an abnormal rhythm in the upper chamber of the heart) is a common supraventricular arrhythmia (a type of abnormal heart rhythm) for which antiarrhythmic therapy is often prescribed. The primary goals of therapy are to maintain sinus rhythm (normal heart rhythm) and to reduce the occurrence of episodes…
Heart
01 Jan 2013
Home Automatic External Defibrillator Trial — HAT
To compare home use of an automatic external defibrillator to the local emergency medical system in survivors of a heart attack. To compare home use of an automatic external defibrillator to the local emergency medical system in survivors of a heart attack.Condition: – Cardiovascular Diseases- Myocardial Infarction- Heart Diseases- Death,…
Bone
01 Jan 2013
Effects of HIV on the Development and Function of Bone Marrow Cells
This study will examine the effects of HIV on bone marrow cells. Various types of cells from bone marrow will be studied to learn which cells become infected with HIV, what changes occur in the number of or growth patterns of the cells, what kinds of proteins the cells make…
Heart
01 Jan 2013
Oral Enoximone vs. Placebo in Advanced Chronic Heart Failure Subjects
To determine if low-dose enoximone therapy is an effective treatment for advanced chronic heart failure. Official Title ESSENTIAL Protocol No. My-021 and Protocol No. My-026, each titled: A Phase III, Randomized, Double-Blind, Multicenter, Parallel Group, Placebo-Controlled Study of Oral Enoximone vs. Placebo in Advanced Chronic Heart Failure Subjects Conditions…
Bone
01 Jan 2013
Spine Patient Outcomes Research Trial (SPORT) – Intervertebral Disc Herniation
This study tests the effectiveness of different treatments for the three most commonly diagnosed lumbar (lower) spine conditions. The purpose of the study is to learn which of two commonly prescribed treatments (surgery and non-surgical therapy) works better for specific types of low back pain. This study tests the effectiveness…
Gastro
01 Jan 2013
Obesity and Free Fatty Acid Flux
This study, conducted at the National Institutes of Health in Bethesda, Maryland, and at the Mayo Clinic in Rochester, Minnesota, will explore obesity among Caucasians and African-Americans by examining the relationship of resting energy expenditure (REE) to fatty acid flux. REE is the rate the body uses calories while at…
Heart
01 Jan 2013
Efficacy and Safety of Azimilide in the Prophylactic Treatment of Patients With Atrial Fibrillation.
Atrial fibrillation (an abnormal rhythm in the upper chamber of the heart) is a common supraventricular arrhythmia (a type of abnormal heart rhythm) for which antiarrhythmic therapy is often prescribed. The primary goals of therapy are to maintain sinus rhythm (normal heart rhythm) and to reduce the occurrence of episodes…
Gastro
01 Jan 2013
Chromium Effects in Impaired Glucose Tolerance
Impaired glucose tolerance(IGT) often precedes Type II diabetes and is a cardiac risk. Chromium (Cr) is an insulin co-factor. This study will investigate the effects of daily Chromium for 6 months at two doses on serum measures of glucose tolerance and endothelial function in adults with IGT. Official Title Conditions…
Heart
01 Jan 2013
Healthy Heart Amputation Rehabilitation Treatment (H.A.R.T)
In the VA, we are achieving progress in decreasing amputation rates through early identification and multidisciplinary treatment of patients at risk for limb loss. Despite these accomplishments, however, clinical outcomes post-amputation, especially for PVD patients, have changed little because of patients’ poor cardiovascular condition complicated by the injurious consequences of…