VMC Migration

Bone 01 Jan 2013

Genetic Determinants of Ankylosing Spondylitis Severity

This study will explore how genes-units of heredity-may influence the severity of ankylosing spondylitis. It will examine whether some genes may cause people with ankylosing spondylitis to have more rapid fusion of the bones of the spine, more difficulty performing daily activities, or be more likely to need joint surgery.
Bone 01 Jan 2013

Study of Arthritis and Related Conditions

The purpose of this study is to learn more about the causes of rheumatoid arthritis, juvenile rheumatoid arthritis and related conditions and the course of these diseases. Patients in this study will not receive treatment, but may be offered participation in a treatment protocol if an appropriate study is available.
Bone 01 Jan 2013

Literacy in Arthritis Management

This study will test a new patient education program designed for people who do not read well. It will also look at how poor reading skills affect a person’s health and how people who do not read well learn best. We will randomly assign patients who have a rheumatic condition…
Blood 01 Jan 2013

Study of Clotrimazole and Hydroxyurea in Patients With Sickle Cell Syndromes

OBJECTIVES: Determine the effectiveness of the combined use of clotrimazole and hydroxyurea on a specific panel of red cell characteristics in patients with sickle cell syndromes. OBJECTIVES: Determine the effectiveness of the combined use of clotrimazole and hydroxyurea on a specific panel of red cell characteristics in patients with sickle…
Blood 01 Jan 2013

Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia

Patients with sickle cell disease have abnormal hemoglobin (the protein in red blood cells that carries oxygen to the body). This abnormality causes red blood cells to take on a sickle shape, producing disease symptoms. Fetal hemoglobin, a type of hemoglobin present in fetuses and babies, can prevent red cells…
Lungs 01 Jan 2013

Ozone and Rhinovirus-Induced Disease in Asthmatics

In the U.S., morbidity associated with human rhinovirus (RV) infection represents a major health problem. In asthmatics, up to 80% of asthma exacerbations are associated with upper respiratory infections. Despite evidence that environmental oxidant pollutants, such as ozone, may increase the severity of viral disease, the mechanisms underlying such an…
Lungs 01 Jan 2013

Effect of Ventilation-Feedback Training on Exercise Performance in COPD

The primary objective of the study is to determine whether individuals with Chronic Obstructive Pulmonary Disease (COPD) who complete ventilation-feedback training combined with a moderately-high intensity exercise and upper body strength program will demonstrate significantly longer exercise duration on a constant work rate treadmill test when compared to subjects who…
Lungs 01 Jan 2013

Role of Role of Genetic Factors in the Development of Lung Disease

This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. Official Title Role of Genetic Factors in the Pathogenesis of Lung Disease Conditions –…
Sample Collections from the Airways of Asthmatic Patients
Lungs 01 Jan 2013

Sample Collections from the Airways of Asthmatic Patients

Fiberoptic bronchoscopy is a procedure which involves passing a pencil-thin tube into the lung in order to collect fluid and cells from the airways. Fiberoptic bronchoscopy can collect cells from the walls of airways by gently brushing them (bronchial brushing). In addition, squirting small amounts of sterile water in to…