Research and Trials
01 Jan 2013
Efficacy and Safety Study of Abatacept to Treat Lupus Nephritis
The purpose of this clinical research study is to learn if abatacept treatment of patients with active lupus nephritis who are also taking mycophenolate mofetil (MMF) and steroids as part of this study will control the nephritis despite a protocol-defined steroid taper; the endpoint is a “complete renal response”, a…
Blood
01 Jan 2013
Trial to Reduce Cardiovascular Events With ‘Aranesp’ Therapy (TREAT)
The purpose of this study is to assess the impact of treatment of anemia with darbepoetin alfa on mortality and cardiovascular morbidity in patients with chronic kidney disease and type 2 diabetes. Official Title Conditions Kidney Disease, Nephritis, Diabetes Mellitus, anaemia Study Type Interventional Study Design Treatment Further Details Primary…
Research and Trials
01 Jan 2013
Study of Long-Term Living Kidney Donors
This study is designed to quantify the long-term medical and psychosocial implications of living kidney donation. The short-term consequences of living donation are well established. On the other hand the long-term consequences of living kidney donation are far less certain. The main medical concerns of living kidney donation include an…
Heart
01 Jan 2013
Telmisartan vs. Losartan for Improvement of Renal Function in Hypertensive Diabetic Patients With Overt Nephropathy.
A number of blood pressure lowering drugs in the class known as angiotensin receptor blockers (ARB) have been shown to slow the decline in kidney function of patients with type 2 diabetes, high blood pressure, and kidney disease. Losartan (COZAAR), is one such drug. The purpose of this research study…
Cancer
01 Jan 2013
SU011248 Versus Interferon-Alfa As First-Line Systemic Therapy For Patients With Metastatic Renal Cell Carcinoma
The purpose of this study is to test whether SU011248 has activity and is safe compared to interferon-alfa as first-line therapy in patients with metastatic renal cell carcinoma (RCC). Official Title A Phase 3, Randomized Study Of SU011248 Versus Interferon-Alfa As First-Line Systemic Therapy For Patients With Metastatic Renal Cell…
Research and Trials
01 Jan 2013
Freedom Study: Myfortic in Kidney Transplant Patients
The primary objective of the study is to evaluate that 3 immunosuppressant regimens will have comparable kidney function results in kidney transplant patients. Official Title Study to Investigate the Clinical Outcomes of Different Regimens of ‘Myfortic’ in De Novo Kidney Tx Pts Using ‘Simulect’ and ‘Neoral’ With or Without Steroids…
Heart
01 Jan 2013
Study of the Effect of Alendronate on Vascular Calcification and Arterial Stiffness in Chronic Kidney Disease
We aim to perform a prospective, randomised study assessing the impact of alendronate on cardiovascular and bone mineral parameters. This will be a single-centre study involving subjects with CKD Stage 3 (those patients with GFR between 30 and 59ml/min). Arterial stiffness (by pulse wave analysis and pulse wave velocity) and…
Research and Trials
01 Jan 2013
A Study of BMS-224818 (Belatacept) in Patients Who Have Undergone a Kidney Transplant and Are Currently on Stable Cyclosporine or Tacrolimus Regimen With or Without Corticosteroids
The purpose of this study is to learn if conversion to belatacept from cyclosporine or tacrolimus will preserve kidney function in people who have had a kidney transplant. The safety of this treatment will also be studied Official Title Belatacept Conversion Trial in Renal Transplantation Conditions Renal Transplant Study Type…
Research and Trials
01 Jan 2013
Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidney
The purpose of this study is to determine which combination of the tablets ramipril, irbesartan or spironolactone is best to lower protein leakage from the kidney. Protein leak from the kidney into the urine is an indicator of kidney damage. The higher the leak, the worse the damage and the…
