Joints

Efficacy Study of Prolotherapy vs Corticosteroid for Tennis Elbow
Chronic Pain 01 Jan 2013

Efficacy Study of Prolotherapy vs Corticosteroid for Tennis Elbow

The purpose of the research is to study the effects of two different injection therapies for the treatment of lateral epicondylitis (tennis elbow). Specifically, we will look at which therapy provides better short and long-term relief of pain, which treatment allows better function and less disability, and which treatment gives…
Intra-Articular Injection of Botulinum Toxin Type A for Shoulder Pain
Chronic Pain 01 Jan 2013

Intra-Articular Injection of Botulinum Toxin Type A for Shoulder Pain

The purpose of this study is to determine whether intra-articular botulinum toxin type A is effective in the treatment of chronic joint pain. Official Title Intra-Articular Injection of Botulinum Toxin Type A for the Treatment of Shoulder Pain: A Randomized, Double Blinded, Placebo Controlled Trial. Conditions Arthritis Shoulder…
Synvisc Injections for Lumbar Facet Joint Pain
Chronic Pain 01 Jan 2013

Synvisc Injections for Lumbar Facet Joint Pain

The objective of this investigation is to evaluate the safety and efficacy of viscosupplementation in treating symptomatic lumbar facet joint arthropathy. The intended use of the device (Synvisc) is to alleviate pain and improve function in patients with painful lumbar facet joint arthrosis by intra-articular injection into the involved joint.
Hormones 01 Jan 2013

PaTH Study: Parathyroid Hormone and Alendronate for Osteoporosis

This 2-year study will test the effectiveness of combining parathyroid hormone (PTH) and alendronate for treating osteoporosis in postmenopausal women. Alendronate is a drug used to treat osteoporosis and primarily prevents bone loss, whereas PTH increases bone formation. We will treat the study participants either with PTH and alendronate, alendronate…
Joints 01 Jan 2013

Influence of Weight Loss or Exercise on Cartilage in Obese Knee Osteoarthritis Patients (CAROT)

Obesity and osteoarthritis (OA) co-exist in an increasing part of the population.The two diseases intertwine in several ways. The evolution in the population shows a tendency towards deterioration of both by increasing general age and weight. The two diseases share pathogenetic features and the development of one disease increases the…
Bone 01 Jan 2013

Abatacept in the Treatment and Prevention of Active Systemic Lupus Erythematosus (SLE) Flares in Combination With Prednisone

The purpose of this clinical research study is to learn whether Abatacept can treat and prevent lupus flares; specifically, active lupus flares in at least one of three organ systems: skin (discoid lesions), inflammation of the lining of the heart (pericarditis), or inflammation of the lining of the lung (pleuritis/pleurisy);…
Bone 01 Jan 2013

Objectives Study in Rheumatoid Arthritis (The OSRA Study)

Rheumatoid synovitis causes largely irreversible damage to cartilage, bone and ligaments. Drug therapy aims to provide symptomatic relief but more importantly to suppress synovitis, or ‘disease activity’, in the hope that this will limit joint damage. Total elimination of disease is a challenging target in any patient and almost unachievable…
Bone 01 Jan 2013

A Study of the Safety and Efficacy of Intravenous CNTO 148 (Golimumab) in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy

The primary purpose of this study is to assess the clinical effectiveness and safety of intravenous (IV- injection directly into the vein) golimumab infusions every 12 weeks in patients with active rheumatoid arthritis (RA) despite current MTX treatment. The secondary objectives of this study are to evaluate the effects on…
Bone 01 Jan 2013

Study Evaluating Etanercept and Sulphasalazine in Ankylosing Spondylitis

The purpose of this study is to compare the efficacy of etanercept and sulphasalazine in the treatment of Ankylosing Spondylitis. Official Title A Randomized, Double-Blind Study Evaluating the Safety and Efficacy of Etanercept and Sulphasalazine in Subjects With Ankylosing Spondylitis Conditions Ankylosing Spondylitis Study Type Interventional Study Design Treatment,…