Chronic Pain

Trial of Physiotherapy and Corticosteroid Injections in Lateral Epicondylalgia
Bone 01 Jan 2013

Trial of Physiotherapy and Corticosteroid Injections in Lateral Epicondylalgia

This randomised controlled trial will evaluate the role of manual therapy and therapeutic exercise and corticosteroid injections in the treatment of lateral epicondylalgia (tennis elbow). Official Title A Pragmatic, Randomised Controlled Trial of Physiotherapy and Corticosteroid Injections in Lateral Epicondylalgia Conditions Tennis Elbow, Musculoskeletal Diseases Study Type Interventional Study Design…
Efficacy Of Pregabalin In Subjects With Post-Stroke Pain
Chronic Pain 01 Jan 2013

Efficacy Of Pregabalin In Subjects With Post-Stroke Pain

Efficacy of pregabalin in subjects with post-stroke pain. Official Title A 13-Week, Randomized, Multi-Centre, Double-Blind, Placebo-Controlled, Parallel-Group, Phase IV Study To Evaluate The Efficacy, Safety And Tolerability Of Pregabalin (150-600 Mg/Day) Using A Flexible Dosing Schedule In The Treatment Of Subjects With Central Post-Stroke Pain (CPSP). Conditions Central Nervous…
ZD4054 in Pain-Free or Mildly Symptomatic Patients With Prostate Cancer and Bone Metastases Who Have Rising Serum Prostate Specific Antigen (PSA)
Cancer 01 Jan 2013

ZD4054 in Pain-Free or Mildly Symptomatic Patients With Prostate Cancer and Bone Metastases Who Have Rising Serum Prostate Specific Antigen (PSA)

This study is being carried out to see if ZD4054 is effective in treating prostate cancer and spread of cancer to the bone, and if so, how it compares with placebo (sugar pill). The study will also provide further information on the safety of ZD4054. Official Title Randomized, Double-Blind, Parallel-Group,…
Pain and Stress Management for People with Rheumatoid Arthritis
Chronic Pain 01 Jan 2013

Pain and Stress Management for People with Rheumatoid Arthritis

Self-management of rheumatoid arthritis (RA) symptoms using written emotional disclosure (ED), coping skills training (CST), or a combination of both may benefit people with RA. The purpose of this study is to determine the benefits of ED, CST, or CST and ED together in adults with RA. This study will…
Ibandronic Acid versus Zoledronic Acid in Cancer Patients with Skeletal Metastases Experiencing Moderate to Severe Pain
Bone 01 Jan 2013

Ibandronic Acid versus Zoledronic Acid in Cancer Patients with Skeletal Metastases Experiencing Moderate to Severe Pain

The purpose of the study is to investigate a new therapy for treating bone pain that results from cancer that has spread to the bones. The study compares treatment with ibandronic acid against treatment with another drug, zoledronic acid (a drug similar to ibandronic acid) to determine which drug is…
Pain Management Techniques for Fibromyalgia
Chronic Pain 01 Jan 2013

Pain Management Techniques for Fibromyalgia

Pain management techniques may influence how the brain processes pain and may help patients with fibromyalgia (FM), a chronic pain condition. This study will train patients with FM to use pain management techniques. Investigators will use brain scanning (functional magnetic resonance imaging, or fMRI) technology to identify changes in how…
New Oral Anticoagulant Therapy for the Prevention of Blood Clots Following Hip or Knee Replacement Surgery
Blood 01 Jan 2013

New Oral Anticoagulant Therapy for the Prevention of Blood Clots Following Hip or Knee Replacement Surgery

LY517717 (a capsule given by mouth) is a blood thinner that may prevent blood clots from forming in the legs and may prevent those blood clots from traveling to the lungs. Leg and lung blood clots occur commonly after patients have surgery to replace a hip or knee joint. These…
Chronic Pain 01 Jan 2013

Positron Emission Tomography to Measure Pain and Pain Control

This study will examine how the brain processes pain signals and how the different parts of the brain work with each other in response to painful stimuli. A better understanding of how people experience pain may be helpful in developing more effective treatments. Healthy normal volunteers, patients requiring third…
Pain Control in Patients With Recurrent or Metastatic Breast or Prostate Cancer
Cancer 01 Jan 2013

Pain Control in Patients With Recurrent or Metastatic Breast or Prostate Cancer

RATIONALE: An outpatient educational and behavioral skills training program may help patients with metastatic breast or prostate cancer live longer and more comfortably. PURPOSE: Randomizedpilot study to evaluate whether an outpatient educational and behavioral skills training program will improve pain control in patients who have metastatic or recurrent breast…