Children's health
01 Jan 2013
An Outpatient Study of the Effectiveness and Safety of Depakote ER in the Treatment of Mania/Bipolar Disorder in Children and Adolescents
The purpose of this study is to determine the safety and effectiveness of Depakote ER (Divalproex Sodium Extended-Release Tablets) compared to placebo in the treatment of bipolar disorder, manic or mixed type in children and adolescents ages 10-17 years. Official Title Conditions Bipolar Disorder Study Type Interventional Study Design Treatment…
Mental Health
01 Jan 2013
Comparison of Intramuscular Olanzapine Depot to Oral Olanzapine and Low-Dose Depot in the Maintenance Therapy of Patients With Schizophrenia
Key objectives of this clinical study are to: – Determine how well intramuscular (IM) olanzapine depot works compared to oral olanzapine – Evaluate the safety and tolerability of IM olanzapine depot compared to oral olanzapine – Evaluate different doses of IM olanzapine depot to identify the best dose(s)…
Children's health
01 Jan 2013
Quetiapine Fumarate (SEROQUEL) Compared to Placebo in the Treatment of Children and Adolescent Patients with Bipolar I Mania
The purpose of this study is to demonstrate efficacy and safety of quetiapine fumarate (SEROQUEL) compared with placebo in the treatment of children and adolescent patients with Bipolar I mania. Official Title Conditions Bipolar Disorder Study Type Interventional Study Design Treatment, Placebo Control, Safety/Efficacy Study Further Details Study Start…
Mental Health
01 Jan 2013
Duloxetine Compassionate Use in Patients Who Have Completed a Previous Neuroscience Duloxetine Clinical Trial
The primary objective of this study is to provide duloxetine to investigators for the treatment of patients who have previously participated in neuroscience duloxetine clinical trials and for whom effective alternative therapy is not available. Official Title Open Label Duloxetine Compassionate Use in Patients Who Have Completed a Previous Neuroscience…
Mental Health
01 Jan 2013
Efficacy and Safety of Aricept in the Treatment of Severe Alzheimer’s Disease
Donepezil hydrochloride (Aricept) has been approved to treat symptoms associated with mild to moderate Alzheimer’s disease (AD). Aricept has been shown to improve the memory and thinking abilities, activities of daily living and global function in patients. The purpose of the study is to further investigate the effectiveness and safety…
Mental Health
01 Jan 2013
Clinical Trial of Pramipexole in Bipolar Depression
The purpose of this study is to examine the safety and effectiveness of the drug pramipexole given in combination with lithium or divalproex for the short-term treatment of acute depression in patients with bipolar disorder. Bipolar disorder is a severe, chronic, and often life-threatening illness. Treatments for acute unipolar…
Mental Health
01 Jan 2013
Psychosocial Treatment for Attention Deficit Hyperactivity Disorder (ADHD) Type I
The purpose of this study is to develop and implement a treatment that focuses on behaviors to reduce symptom severity and functional impairment in patients with Attention Deficit Hyperactivity Disorder, Predominantly Inattentive Type (ADHD-I). The long-term goal of this study is to apply the treatment to larger-scale trials to determine…
Mental Health
01 Jan 2013
Ginkgo Biloba: Antidepressant-Induced Sexual Dysfunction
The purpose of this study is to provide the first empirical examination of the effects of Ginkgo biloba (GBE), sex therapy, and a combination of the two on subjective and physiological measures of sexual function in women who are experiencing sexual disorders secondary to antidepressants. Official Title Conditions – Hypoactive…
Bone
01 Jan 2013
Bone Mineral Density in Women with Major Depression
The purpose of this study is to examine calcium absorption and bone mineral density in women with depression. Research indicates that pre-menopausal women with depression have significantly lower bone mineral density (BMD) than pre-menopausal women without depression. Although the mechanisms of BMD loss are unclear, researchers believe that individuals with…
