BRCA1 is a gene which, when damaged (mutated), places a woman at greater risk of developing breast and/or ovarian cancer, compared with women who do not have the mutation. In a woman with a BRCA1 mutation, the estimated lifetime risk of developing breast cancer is about 50% compared with 12% in the general population. A person who has this mutated gene has a 50% chance of passing on the gene to each of her children.
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