Cancer
01 Jan 2013
BMS-354825 in Patients With Chronic Accelerated, or Blast Phase Chronic Myelogenous Leukemia or Philadelphia Positive Acute Lymphoblastic Leukemia
The purpose of this clinical research study is to understand the safety and efficacy of BMS-354825 in patients with chronic, accelerated, or blast phase chronic myelogenous leukemia (CML) or Philadelphia positive acute lymphoblastic leukemia (ALL) who are resistant to or intolerant of imatinib mesylate (Gleevec). Official Title Phase I Study…
Research and Trials
01 Jan 2013
Effect of Pantoprazole on the Symptoms of Acid Reflux Disease in Adult Patients (BY1023/M3-341)
The aim of the present study is to identify factors (such as symptom patterns and symptom scores) that influence the response to treatment with pantoprazole using different evaluation methods (e.g. ‘ReQuest’ questionnaire, patient and investigator assessment). Pantoprazole will be administered once daily in the morning at one dose level. The…
Cancer
01 Jan 2013
Cisplatin Plus Gemcitabine With or Without Paclitaxel in Treating Patients With Stage IV Urinary Tract Cancer
Randomized phase III trial to compare the effectiveness of cisplatin plus gemcitabine with or without paclitaxel in treating patients who have stage IV urinary tract cancer. Official Title Randomized Phase III Study Comparing Paclitaxel/Cisplatin/Gemcitabine and Cisplatin/Gemcitabine in Patients With Metastatic or Locally Advanced Urothelial Cancer Without Prior Systemic Therapy…
Research and Trials
01 Jan 2013
Safety Study of Herpes Simplex Vaccine in HSV Seronegative and Seropositive Females Between 10 and 17 Years Old
Main goal of this study is to compare the occurrence of serious adverse events (SAEs) between the herpes simplex (gD2-AS04) vaccine group and the Saline control group throughout the study period (up to month 12). Official Title A Study to Evaluate the Immunogenicity and Safety of GlaxoSmithKline Biologicals Herpes Simplex…
Research and Trials
01 Jan 2013
Isavuconazole in the Treatment of Candidemia and Other Invasive Candida Infections
The purpose of the study is to compare the safety and efficacy of Isavuconazole versus caspofungin followed by voriconazole in the treatment of candidemia and other invasive Candida infections. Official Title A Phase III, Double-Blind, Randomized Study to Evaluate the Safety and Efficacy of Isavuconazole Versus Caspofungin Followed by Voriconazole…
Research and Trials
01 Jan 2013
EMPOWER Clinical Trial: Vagal Blocking for Obesity Control
This is a randomized multi-center study being done to measure the ability of a new medical device, Maestro System, to safely reduce body weight over five years in people who are considered obese. Official Title EMPOWER Clinical Trial: Vagal Blocking for Obesity Control Conditions Obesity Study Type Interventional Study Design…
Research and Trials
01 Jan 2013
A Study to Determine the Long-Term Efficacy and Safety of Ramelteon in Adults With Chronic Insomnia.
The study will involve an evaluation of the efficacy and safety of ramelteon (TAK-375) over a 6-month period in adults and elderly subjects with chronic insomnia. The test agent ramelteon will be used at 8 mg fixed dose and the study will be conducted in multiple sites. Official Title A…
Research and Trials
01 Jan 2013
The Neurobiology of Depressive Illness
We aim to determine why patients with depression are at an elevated risk for the development of coronary heart disease, and resolve whether the severity of a patient’s depression has a counterpart in demonstrable abnormalities in brain chemistry. Official Title The Neurobiology of Depressive Illness: Causes and Consequences of Altered…
Research and Trials
01 Jan 2013
Effect of the ‘Mother and Baby’ Program on Well-Being
The study investigates the effect of the ‘Mother and Baby’ (M&B) program on the psychological health and well-being of new mothers 6-10 weeks following the birth of their baby. The M&B program is an 8-week program of group exercise and education sessions provided by various health professionals. The design of…
