Gastro
01 Jan 2013
Barrett’s Esophagus Early Detection Study
The incidence rate for esophageal adenocarcinoma (EAC) has risen 10% per year over the past two decades and is the most rapidly increasing cancer in the U.S. Potential reasons for this increase include obesity and gastroesophageal reflux disease (GERD). Prevention strategies to date have focused on early detection. Barrett’s esophagus…
Mental Health
01 Jan 2013
Preventing the Recurrence of Depression with Drugs and Psychotherapy
The purpose of this study is to determine whether the addition of Cognitive Therapy (CT) to antidepressant medication (ADM) enhances treatment for depression. This study will also test whether the addition of CT to ADM will prevent recurrences of depression after therapy is over. Official Title Prevention of Recurrence in…
Gastro
01 Jan 2013
Peg-Intron for Prevention of Disease Progression in Chronic Hepatitis C Patients with Cirrhosis (failing with Interferon plus Ribavirin treatment)
The objective of the study is to evaluate the safety and efficacy of PEG-Intron vs. no treatment for the prevention of disease progression in adult subjects with compensated cirrhosis secondary to chronic hepatitis C, who failed to respond to therapy with an a interferon plus ribavirin. Official Title Peg-Intron for…
Cancer
01 Jan 2013
Exemestane Compared With Anastrozole, With or Without Celecoxib, in Treating Postmenopausal Women After Surgery for Primary Breast Cancer
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using exemestane or anastrozole may fight breast cancer by reducing the production of estrogen. It is not yet known whether exemestane is more effective than anastrozole, with or without celecoxib, in preventing the recurrence of breast cancer. RATIONALE:…
Cancer
01 Jan 2013
Adjuvant Tamoxifen Compared With Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using either tamoxifen or anastrozole may fight breast cancer by blocking the uptake of estrogen. It is not yet known whether tamoxifen is more effective than anastrozole in preventing breast cancer after surgery for ductal carcinoma in situ.
Mental Health
01 Jan 2013
Propranolol for the Treatment of Acute Stress Disorder
This 10-week study will examine whether propranolol, a medication that blocks the activity of the stress hormones adrenaline and noradrenaline, can relieve acute stress disorder (ASD) and symptoms from persisting long-term. ASD is a condition that some people develop soon after exposure to trauma. They may be anxious, depressed, have…
Mental Health
01 Jan 2013
Role of Dopamine in Response to Alcohol
This study will examine the role of the brain chemical dopamine in people’s response to alcohol consumption. Dopamine is thought to influence whether people have a strong or weak response to alcohol and how pleasurable that response is. The findings of this study may shed light on why some people…
Gastro
01 Jan 2013
Cognitive Therapy for Binge-Eating Disorder
The purpose of this study is to compare the efficacy of a CD-ROM-based cognitive-behavioral therapy (CBT) to traditional manual-based group therapy for obese individuals with binge-eating disorder (BED) and other unhealthy eating behaviors. A second goal is to encourage a healthy lifestyle in patients with BED. Official Title Cognitive Therapy…
Lungs
01 Jan 2013
Treatment of Pulmonary Sarcoidosis with Pentoxifylline
Sarcoidosis is a disease most commonly affecting the lungs, but it can also involve lymph nodes, skin, liver, spleen, eyes, bones, and glands. The cause of the disease is unknown. When it occurs it can produce an inflammatory reaction leading to irreversible organ damage and disability. Official Title Conditions –…
