Bone
01 Jan 2013
EVA: Evista Alendronate Comparison
The purpose of this study is to determine how treatment with raloxifene compares to treatment with alendronate in postmenopausal women with osteoporosis on the chance of experiencing fractures The purpose of this study is to determine how treatment with raloxifene compares to treatment with alendronate in postmenopausal women with osteoporosis…
Bone
01 Jan 2013
Nitroglycerin Ointment for Preventing Bone Loss in Postmenopausal Women
Osteopenia and osteoporosis cause thinning of bone tissue and loss of bone density over time. The purpose of this study is to determine the safety and effectiveness of nitroglycerin ointment for the treatment of osteopenia in postmenopausal women. Official Title Prevention of Postmenopausal Bone Loss with Nitric Oxide Conditions –…
Bone
01 Jan 2013
Vertebroplasty for the Treatment of Fractures Due to Osteoporosis
Vertebroplasty is a procedure used to stabilize broken vertebrae, the bones that form the spine. This study will evaluate the effectiveness of vertebroplasty for the treatment of fractures due to osteoporosis. Official Title Investigational Vertebroplasty Efficacy and Safety Trial (INVEST) Conditions – Spinal Fractures- Osteoporosis Study Type Interventional Study…
Bone
01 Jan 2013
Studies on Abnormal Bone from Patients with Polyostotic Fibrous Dysplasia and McCune Albright Syndrome
This study will investigate how a gene mutation (change in DNA) causes the abnormal bone in fibrous dysplasia-a condition in which areas of normal bone are replaced with a fibrous growth similar to a scar. The bone abnormalities in fibrous dysplasia can occur in a single bone (monostotic fibrous dysplasia),…
Bone
01 Jan 2013
Bone Mineral Density in Women with Major Depression
The purpose of this study is to examine calcium absorption and bone mineral density in women with depression. Research indicates that pre-menopausal women with depression have significantly lower bone mineral density (BMD) than pre-menopausal women without depression. Although the mechanisms of BMD loss are unclear, researchers believe that individuals with…
Bone
01 Jan 2013
Bone Regeneration Using Stromal Cells
This study will evaluate the possible use of bone marrow stromal cells-a type of cell related to bone and fibrous tissue-for jaw bone grafting. When a tooth is lost or removed, there is usually a gradual loss of bony tissue from the jawbone at the site of the missing tooth.
Mental Health
01 Jan 2013
Behavioral Treatment, Drug Treatment, and Combined Treatment for Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to determine the effectiveness of behavioral treatment, drug treatment, and combined treatment for children with Attention Deficit Hyperactivity Disorder (ADHD). This study will also examine the interactions between different levels of behavioral and drug treatments. Official Title ADHD Treatment: Comparative and Combined Dosage Effects…
Cancer
01 Jan 2013
Vaccine Treatment for Advanced Melanoma
This study will examine the safety and effectiveness of treatment with an experimental vaccine for melanoma, a type of cancer that arises from pigmented areas, usually of the skin. Melanoma tumors produce a protein called gp100. Vaccination with this protein may boost the immune system’s fight against the cancer. The…
Bone
01 Jan 2013
Genetic Determinants of Ankylosing Spondylitis Severity
This study will explore how genes-units of heredity-may influence the severity of ankylosing spondylitis. It will examine whether some genes may cause people with ankylosing spondylitis to have more rapid fusion of the bones of the spine, more difficulty performing daily activities, or be more likely to need joint surgery.